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Vitamin C (ascorbic acid) may help reduce anxiety. It decreases stress reactivity and can help you stay calm. A vitamin and mineral supplement may also be helpful. One study examined the relative effectiveness of a vitamin and mineral supplement and a placebo (sugar pill). The researchers found that as compared to placebo, the supplement was associated with significant reductions in anxiety and perceived stress. Lysine is another supplement that has been shown to reduce chronic anxiety and lessen stress. Many people find some relief at 500 mg a day.

If you’re anxious, it could be because you have a B-vitamin and magnesium deficiency. B vitamins (as well as vitamin C) are rapidly depleted during stressful and anxiety-ridden situations. All these supplements are relatively safe, have few side effects, and are low in cost.
Gamma-aminobutyric acid (GABA) is an amino acid (protein precursor) that acts as a neurotransmitter in your central nervous system and is formed in the body from another amino acid, glutamic acid. GABA inhibits nerve cells from overfiring. Together with niacinamide and inositol (two B vitamins) they prevent anxiety- and stress-related messages from reaching your brain.

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GABA can be taken to calm you in much the same way as a tranquilizer, but without fear of addiction. Note that if you take too much it can increase anxiety and make you short of breath, numb around the mouth, and tingly in the extremities. A helpful level is 750 mg twice a day.
Chromium deficiency can produce anxiety symptoms. Daily take 200 meg.

The amino acid L-glutamine has a mild tranquilizing effect. Take it on an empty stomach at a dose of 500 mg three times a day. Never take it with milk. Use water or juice, and for better absorption add 50 mg vitamin B6 and 100 mg of vitamin C.

Another amino acid, L-tyrosine, may also relieve anxiety and depression, but avoid this supplement if you are taking an MAOinhibitor drug. The usual dose is 500 mg three times a day on an empty stomach. Consider taking it in concert with L-glycine (500 mg three times daily) on an empty stomach.